The people with following conditions should be cautious with this medication. Check with your doctor before consumption if you have any of the accompanying:


  • Asthma
  • Depression
  • drug abuse
  • alcohol intoxication
  • alcoholism
  • serotonin syndrome
  • seizures
  • opioid overdose
  • benzodiazepine overdose
  • CYP2D6 ultrarapid metabolizer
  • CYP2D6 poor metabolizer
  • sleep apnea due to airway obstruction
  • surgical removal of the adenoids in pediatric patient
  • surgical removal of the tonsils in pediatric patient
  • decreased lung function
  • a type of disorder with high serotonin levels
  • a low seizure threshold
  • suicidal behavior
  • suicidal thoughts
  • symptoms from alcohol withdrawal
  • decreased function of the adrenal gland
  • hardening of the liver
  • blockage of the stomach or intestine
  • a mother who is producing milk and breastfeeding
  • life-threatening withdrawal reactions
  • high pressure within the skull
  • nervous system infection of brain and spinal cord
  • chronic obstructive pulmonary disease
  • kidney disease with likely reduction in kidney function


  • Opioids – Morphine Analogues
  • Tramadol

Note*  In case you have consumed having the above conditions followed, immediately call for emergency service or consult to a doctor

WHO TO USE: The data right now planned to enhance, not fill in for, the ability and judgment of medicinal services experts. The data isn’t intended to cover every conceivable use, headings, safety measures, medicate co-operations or unfavorable impacts, nor should it be translated to show that utilization of a specific medication is sheltered, proper or compelling for you or any other individual. A medicinal services proficient ought to be counseled before taking any medication, changing any eating routine or beginning or ceasing any course of treatment.

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